The Mycobacterium tuberculosis Ser/Thr kinase PknB has been implicated in the regulation of cell growth and morphology in this organism.The extracytoplasmic domain of this membrane protein comprises four penicillin binding protein and Ser/Thr kinase associated (PASTA) domains, which are predicted to bind stem peptides of peptidoglycan.Using a compr
This paper presents a fracture mechanical approach for Keychains estimation of critical bending load of different types of aluminum-epoxy flanging and comparison with experimental measurements.For this purpose, several designs of the flanges were investigated.The flanges were glued to the epoxy bars and adhesive-epoxy interface was considered as a
Abstract The bronze doors of the Basilica of San Zeno in Verona, Italy, are a special case in art history research.They were made by several workshops during the twelfth century: stylistically, two to three workshops were assumed to produce Denim Shorts the metal parts of the door.However, it is still unclear when exactly and if this interpretation
Horizontally acquired genes typically function as autonomous units conferring new abilities when introduced into different species.However, we reasoned that proteins preexisting in an organism might constrain the functionality of a horizontally acquired gene product if it operates on an ancestral pathway.Here, we determine how the horizontally acqu